Wednesday, June 12, 2024

Clean & Clear Persa-Gel 10

Clean & Clear Persa-Gel 10 Review

Acne Treatments

Product Grade
Report Card Grade
0 Reviews
Best Feature:
High concentration of benzoyl peroxide is very effective
Worst Feature:
Benzoyl peroxide can be drying and bleaches fabric
Best Uses:
OTC treatment for mild to moderate acne

Where to Buy

Store Name


CLEAN & CLEAR PERSA-GEL 10 is an acne medicine that uses Benzoyl Peroxide to destroy acne-causing bacteria below the surface of your skin to eliminate and prevent breakouts. Originally created as a doctor-prescribed medicine, PERSA-GEL 10 contains the maximum amount of Benzoyl Peroxide (10%) allowed in an over-the-counter formula and is recommended by pharmacists for the treatment of mild to moderate acne.

You can purchase PERSA-GEL 10 at your local drugstore or online at for about $6.49.

Product Report Card Grade

We give Clean & Clear’s Persa-Gel 10 a B+ because it is a very effective and affordable OTC acne treatment for mild to moderate acne. It is almost like getting a prescription-grade medicine without taking a trip to the dermatologist. We had to deduct points, however, because many customers felt that the gel was drying and were annoyed that the Benzoyl Peroxide bleached any fabric that it touched.

This Product
Overall Score
Our Awards
Date Reviewed
February 2012
April 2013
April 2013
inexpensive; very effective treatment that contains the maximum amount of Benzoyl Peroxide allowed in an OTC acne medication
enhances effectiveness of current acne treatment routine and is gentle on skin; convenient size for traveling; 100% natural; good for reducing redness and inflammation
inexpensive; effective treatment of mild acne and blackheads; 3-1 makes nightly routine easier
Benzoyl Peroxide can bleach hair and dyed fabric (clothing, carpet, sheets/pillows, towels, etc.); skin will be more sensitive to outside irritants/sun; tested on animals
time-consuming; expensive (especially if you end up buying the "Power Pack")
won't fade acne scaring; fragrance and coloring agents may irritate sensitive skin; may be overly drying for some users
Active Ingredient or Technology
Gel contains 10% Benzoyl Peroxide.
Device uses phototherapy.
Gel contains 2% Salicylic Acid.
Skin Concern
Mild to moderate acne
Mild to moderate acne
Mild acne and blackheads
Skin Type
Normal, Oily or Combination
Normal, Dry, Oily, Combination, Sensitive
Normal, Oily or Combination
Prescription Needed?
1 fluid ounce
Device is 6.5" tall and the head is 1.25" in diameter. It weighs less than 8 ounces.
2 fluid ounces
Varies based on usage
Varies based on usage
How It Works
Benzoyl Peroxide increases cell turnover to unclog pores and destroys acne-causing bacteria below the surface of your skin to eliminate and prevent future breakouts.
Releases wavelengths of blue light that penetrate deep into your skin to kill acne-causing bacteria, P. acnes, and soothe inflammatory acne vulgaris. Basically, within P. acnes bacteria, there are small molecules known as porphyrins. When exposed to 420 nm and shorter wavelengths of light, porphyrins generate free radicals that attack and kill P. acnes bacteria.
Powerful MicroClearâ„¢ technology helps the key acne medicine, salicylic acid, unclog congested pores and penetrate deep under the surface of your skin to fight acne at its source. At the same time, the unique formula contains moisturizers to hydrate and soften skin, as well as calming ingredients to reduce redness and irritation.
Side Effects
Increased dryness and irritation are possible side effects.
Increased dryness and peeling are possible side effects.
Warranty/Money Back Guarrantee
5-year warranty and 60-day money back guarantee

ProductReportCard Editors' In-Depth Review

Pros And Cons


  • High amount of Benzoyl Peroxide that is an effective medication for treating stubborn cases of acne
  • Inexpensive
  • Over the counter treatment
  • Fragrance-free


  • Benzoyl Peroxide can bleach hair and dyed fabric (clothing, carpet, sheets/pillows, towels, etc.)
  • Benzoyl Peroxide can make your skin more susceptible to sunburns
  • Shouldn't use in conjunction with other topical acne treatments because it could increase dryness or irritation of the skin
  • Tested on animals

Key Features

1.0 fluid ounce
Skin Type
Oily, Normal or Combination (not appropriate for very sensitive skin)
Skin Concern
Mild to moderate acne and stubborn breakouts
How it works
It is a clear gel with a micronized formula that allows the acne medicine to penetrate deep within your pores to stop pimples at the source. 10% Benzoyl Peroxide is the most potent form of this acne medicine available without a prescription.
After washing your face, apply a thin layer of medicine to the entire affected area. You can apply 1-3 times daily, but you are probably better off starting with once daily to see how your skin reacts and gradually increasing your usage from there. If your skin starts to get really dry or peel, just reduce your applications to once a day or every other day.
Prescription Needed?
Key Ingredients
Benzoyl Peroxide 10.0%
All ingredients
Carbomer, Disodium EDTA, Hydroxypropyl Methylcellulose, Laureth-4, Sodium Hydroxide, Water


CLEAN & CLEAR PERSA-GEL 10 receives good reviews on (7.4/10 out of 229 reviews), on (3.8/5 out of 115 reviews) and on (3.9/5 out of 51 reviews). Most of the negative reviews had to do with how drying the medication can be. Paula Begoun, a skincare and cosmetics expert who conducts reviews on products using scientific research, found Persa-Gel 10 was "exceptional" compared to other acne treatments and gave it the "Paula's Pick" award. If you have stubborn acne and your skin isn't very sensitive, this could be a good over-the counter option to try before heading to the dermatologist.


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